uFluidix
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In 2016, the US Defense Advanced Research Projects Agency - DARPA told eight research groups that their proposals had made it through the review gauntlet and would soon get a few million dollars from its Biological Technologies Office (BTO). Along with congratulations, the teams received a reminder that their award came with an unusual requirement an independent shadow team of scientists tasked with reproducing their results. Find out what happened next at https://www.nature.com/articles/d41586-020-00672-7 #microfluidics #reproducibility #research #science

The liver is an important organ with key roles in metabolism that affects the PK-PD response of the drugs. Thus, here we have provided a short review of the potential of microfluidic technology in developing microphysiological systems (MPS) for mimicking the metabolic activities of the liver, also called Liver Chips, in response to a new drug formulation. Find out more about microfluidic Organ-On-a-Chip devices for more accurate drug toxicity screening in preclinical settings at http://bit.ly/33sQ746 #microfluidics #OrganOnAChip #drugtoxicity #drugtesting #LiverOnAChip

New method of bioprinting uses aspiration of tiny biologics such as spheroids, cells and tissue strands, to precisely place them in 3D patterns either on scaffolding or without to create artificial tissues with natural properties, according to Penn State researchers. Penn State ESM National Science Foundation (NSF) National Institutes of Health (NIH) ... Find out more information about new method of bioprinting at https://news.psu.edu//machine-sucks-tiny-tissue-spheroids- #microfluidics #bioprinting #3dprinting #OrganOnAChip

regnancy success as a result of in-vitro fertilisation (IVF) could improve due to research using organ-on-a-chip technology. Dr. Virginia Pensabene is inserting real cells into a silicone chip in order to grow organs to investigate fertility problems. Dr. Pensabene is collaborating with scientists globally to further her research into growing organs-on-chips, with the aim of improving the efficacy of IVF procedures. Currently, the success rate of IVF is as low as 30%. Univers...ity of Leeds School of Computing, University of Leeds Read more about how using organs-on-chip technology can help solve fertility problems at https://eps.leeds.ac.uk//growing-organs-chips-improve-preg #microfluidics #IVF #fertilisation #OrganOnAChip

Researchers of Sechenov University together with their colleagues from Australia used the microfluidics technology to develop a device able to isolate cancer cells from urine of patients with prostate cancer. The study showed high sensitivity and specificity of the new method in diagnosing prostate cancer. The full-text research: https://www.mdpi.com/2072-6694/12/1/81/htm Macquarie University ... UTS: University of Technology Sydney Find out more information at https://www.genengnews.com//prostate-cancer-detection-get/ #microfluidics #prostatecancer #cancer #medicine

The membrane surrounding cells acts as a selective barrier, cradling and protecting the cell’s contents from the external surroundings and choosing which substances to allow in or out of the cell. Scientists have therefore struggled to engineer efficient methods of delivering nanomaterials, such as DNA, proteins and drugs, into cells. Now, researchers from Korea University, in collaboration with the OIST Okinawa Institute of Science and Technology Graduate University, have de...veloped a rapid and efficient delivery method that uses the power of a tiny fluid vortex to deform the cell membranes. Find more about the research at https://www.oist.jp//caught-spin-spiral-vortices-streamlin #microfluidics #nanomaterials #nanofluids #DNA #RNA #CRISPR

Guoan Zheng, a UConn professor of biomedical engineering, recently published his findings on a successful demonstration of a lensless on-chip microscopy platform in @Lab on a Chip. This platform eliminates several of the most common problems with conventional optical microscopy and provides a low-cost option for the diagnosis of disease. UConn School of Engineering UCONN Chemical and Biomolecular Engineering ... Find more information about the research at https://today.uconn.edu//lensless-chip-microscopy-platfor/ #microfluidics #microscopy #LabOnAChip #diagnostics

Tracking the chemicals in the environment in a fully integrated manner is challenging. Pathogen diagnosis also has its own challenges and each pathogen can be detected differently than the others. Microfluidic-based devices for point-of-care applications have been showing promising results for both environmental monitoring of the microorganisms and chemicals as well as pathogen detection. Read more about why microfluidic point of care devices are ideal choices for detecting c...ontaminants in the environment as well as pathogen detection in bodily fluids at http://bit.ly/3aFtqMH #microfluidics #PointOfCare #POC #environment #pollutants #pathogen #detection #diagnostics uFluidix

Researchers in the UK claim to have developed a microfluidic chip that can rapidly tell whether someone has suffered a traumatic brain injury from a finger-prick blood sample. The optofluidic device detects a biomarker linked to brain injury, based on the way that it scatters light. The full-text article: http://ow.ly/qoDB50yGGoi University of Birmingham ... Queen Elizabeth Hospital Birmingham Read more about the research at http://ow.ly/EspL50yGGof #microfluidics #optofluidics #braininjury #biomarker

The researchers from Purdue University engineered a 'time machine' to understand pancreatic cancer better and found that it is more unpredictable than known. When cancer cells grow together, they promote each other's growth, the researchers found. Other than the discoveries made during the publication of the paper, that provided new insights into the evolution of the disease, the researchers have found drug resistance in types of cancer cells arising from two-drug sensitive o...nes. Purdue Biological Sciences Purdue University Mechanical Engineering Find out more information about a 'time machine' at https://www.purdue.edu//pancreatic-cancer-time-machine-exp #microfluidics #pancreaticcancer #cancer #drugresistance #cancerresearch #medicine

Current tests for male fertility include measuring the concentration and motility of spermatozoa. However, other characteristics of sperm, such as their ability to follow a chemical trail to the egg, can influence the likelihood of fertilization. Now, researchers have devised a quick and convenient microfluidic chip to assess this chemotactic response of spermatozoa, which could help provide a more complete picture of a man’s fertility. University of Twente MESA+ - Institute ...for Nanotechnology The full-text research article: https://pubs.acs.org/doi/full/10.1021/acs.analchem.9b05183 Read more about a simple, easy to fabricate and handle, flow-free microfluidic chip at https://www.acs.org//acs-presspac-february-19-2020/new-way #microfluidics #malefertility #fertility #medicine #research

Micro/nanofibers have gained a lot of attention lately due to their extensive applications in tissue engineering and regenerative medicine. The advent of microfluidic technology also revolutionized the techniques for generating microfibers allowing precise control over the morphology, material, size, and structural anisotropy as well as the biological application of these microfibers. Find out more information about microfluidic technology for versatile fabrication of microfibers and microparticles at http://bit.ly/2Tnx4VN #microfluidics #applications #tissueengineering #microchips #microfibers #microparticles

In a new study on Science Advances, An Li and a research team in the Institute of Chemistry and the University of Chinese Academy of Sciences in China proposed to develop a magnetic-actuated robot. The construct had adjustable structures to distribute forces of resistance and determine droplet behavior. The robot could transport, split, release and rotate droplets for universal applications in various fields and rough environments. The new findings offer an efficient strategy for automated droplet manipulation. Read more at https://phys.org//2020-02-programmable-droplet-magnetic-ac #microfluidics #droplets #drugdelivery #magnetic #robotics

A team of Rice University engineers has introduced the first neural implant that can be both programmed and charged remotely with a magnetic field. Their breakthrough may make possible imbedded devices like a spinal cord-stimulating unit with a battery-powered magnetic transmitter on a wearable belt. Rice Engineering ... Find more information about the implant at https://news.rice.edu//magnet-controlled-bioelectronic-im/ #microfluidics #wearables #implantes #biomedicalengineering #medicaldevices #health