Centre for Molecular Medicine and Therapeutics
950 West 28th Avenue V5Z 4H4 Vancouver, BC, Canada

The latest volume of Human Gene Therapy features the research findings published by the joint effort of the Simpson and Wasserman labs at Centre for Molecular Medicine and Therapeutics. Figure caption: In vivo fundus autofluorescence (FAF) demonstrated intense expression (white) in the perifoveal ring, optic nerve, and nerve fibers.

The Simpson and Wasserman labs used computational biology and mined the human genome for the best genes from which to develop a novel minimal promoter element(s) designed for expression in restricted cell types (MiniPromoter) to improve the safety and efficacy of retinal ganglion cell gene therapy. To read more about their latest exciting findings: https://www.liebertpub.com/doi/10.1089/hum.2018.118... Centre for Molecular Medicine and Therapeutics #genetherapy #Bioinformatics

Four positions available in the Wasserman lab to work in the enticing Silent Genomes Project (https://www.bcchr.ca/silent-genomes-project):

Tune in to Global BC tonight around 6:30 pm for Linda Aylesworth's story on the latest research that could help guide personalized treatments for kids with canc...er. She talks with Gloria Cuccione as well as investigators at the Michael Cuccione Foundation Childhood Cancer Research Program, Dr. Chris Maxwell and Dr. Phillipp Lange, at BC Children's Hospital. Full story here: bit.ly/2sIOLkf See more

Recently published in FASEB journal, the Hayden Lab identified a novel caspase protease site that regulates mutant HTT aggregation, indicating caspase-1 might be target to promote mutant HTT clearance in Huntington disease. #huntingtondisease

November is Crohn's Disease and Colitis Awareness Month. In the Vallance Lab at BC Children’s Hospital, research on the intestinal epithelium - a layer of tissu...e just one cell thick - is leading to insights that might improve care for kids with these painful, chronic conditions. Learn more: bit.ly/2N6vtlx See more

New Times Higher Education global subject rankings have been released, with UBC at 26 in Life Sciences, 52 in Physical Sciences, 12 in Psychology and 30 in Pre-clinical, Clinical & Health. http://ow.ly/as9R30mxqid

The Department of Medical Genetics is holding their annual Research Day at Life Sciences Institute tomorrow (Nov 9th), please see poster below for detail: University of British Columbia UBC Faculty of Medicine

How do vaccines work at a population level? How can Canadians address health inequities beyond our own borders? Check out the video of Dr. Julie Bettinger's and Dr. Gina Ogilvie's presentations from last week's Mini Med School to learn about these topics and more:bit.ly/2OZb1DW

The UBC Department of Medicine Research Expo is coming up next week on November 7, 2018. This event features an exciting program of talks, posters and networking opportunities. Register by November 1! Read more: bit.ly/2qh1KbG

#CBR_UBC seminar this Wednesday at 12 pm at LSC3; Dr. Elizabeth M. Simpson from Centre for Molecular Medicine and Therapeutics: "CRISPR for Gene Therapy and Novel Mouse Models"

Dozens of children across the United States have contracted "acute flaccid myelitis", characterized by the loss of muscle control in the arms or legs. A poliolike virus may be the culprit: