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Locality: Toronto, Ontario
Address: 460 Richmond St W Suite 602 M5V1Y1 Toronto, ON, Canada
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Scientists engineer atomic lattices with a predetermined electrical response by moving individual atoms. Illustrated is the tip of a scanning tunnelling microscope (STM) above chlorine atoms that have been deliberately moved. Drost et al. Nature Physics 2017 Credit: Ella Maru Studio & Aalto University Source: http://www.nature.com//j/vaop/ncurrent/full/nphys4080.html
Scientists discover that activating the host enzyme sirtuin 1 can reduce the growth of drug-susceptible and drug-resistant Mycobacterium tuberculosis, ameliorate lung pathology, and potentiate the efficacy of isoniazid in mice infected with M. tuberculosis. Shown is a macrophage (red) engulfing tuberculosis bacteria (yellow) Cheng et al. Science Immunology 2017. Credit: ZEISS Microscopy Source: http://immunology.sciencemag.org//10.11/sciimmunol.aaj1789
Scientists reveal that lungs constitute a reservoir for megakaryocyte progenitor cells and blood stem cells, accounting for 50% of total platelet production. Shown is a confocal immunofluorescent micrograph of primary #megakaryocytes. Lefrançais et al. Nature 2017. Credit: Hornstein Lab. Source: http://www.nature.com//journal/vaop//full/nature21706.html
Scientists use genotyping data to devise a polygenic hazard score to identify and stratify risk for developing Alzheimer’s disease. Shown is a 3D reconstruction of an immune cell (red) containing -amyloid (blue) within an intracellular degradation compartment (yellow). Desikan et al. PLoS Medicine 2017. Marie-Victoire Guillot-Sestier, PhD. Source: http://journals.plos.org/plosmedicine/article
Scientists report that a single dose of inclisiran, PCSK9-specific RNA interference therapy, reduced participants’ LDL #cholesterol levels by 51 percent. Shown is an illustration of an atherosclerotic plaque deposit. Ray et al. New England Journal of Medicine 2017 Credit: Intermountain Medical Center Source: http://www.nejm.org/doi/full/10.1056/NEJMoa1615758
Scientists employ single-particle cryo-electron microscopy and mass spectrometry to uncover how the #cyanobacterial Kai system assembles to control the circadian clock. Shown are cyanobacterial cells. Snijder et al. Science 2017. Credit: Ducat Lab. Source: http://science.sciencemag.org/c/doi/10.1126/science.aag3218
Scientists devise a paper-based #blood test that can determine blood type in seconds and with more than 99.9% accuracy. Shown is a computer graphics depiction of a human red blood cell on a glass surface. Zhang et al. Science Translational Medicine 2017. Credit: Rogeriopfm | Wikimedia Commons. Source: http://stm.sciencemag.org//doi/10.1126/scitranslmed.aaf9209
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