Next Level Fitness NL

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Acute sleep loss in humans leads to a gain in fat mass and loss of muscle mass due to a disrupted circadian clock that dysregulates metabolism in adipose tissue... and decreases structural proteins in skeletal muscle. This study specifically showed that acute sleep loss (an all-nighter) is associated with a decrease in glucose metabolism in skeletal muscle, whereas this pathway is increased in adipose tissue. These data support other data suggesting that sleep loss may lead to a catabolic state in skeletal muscle. While this study studied the effects of 24 hours of sleep deprivation, other studies have suggested that sleep quality and quantity are also important for metabolic health.

Repeated exposure to heat therapy for 6 days increased biomarkers of mitochondrial biogenesis, increased mitochondrial function by 28%, and boosted heat shock p...rotein 70 by 45% in healthy volunteers. This study shows that mitochondrial adaptation occurs in human skeletal muscle in response to repeated exposures to mild heat stress. Exercise, which also increases core body temperature, has also been shown to increase mitochondrial biogenesis. Interested in learning more about the potential advantages of periodic heat stress? Check out the following FoundMyFitness episodes... Hyperthermic Conditioning for Hypertrophy, Endurance, and Neurogenesis https://www.youtube.com/watch?v=aHOlM-wlNjM How Sauna Use May Boost Longevity https://www.youtube.com/watch?v=eWKBsh7YTXQ Dr. Jari Laukkanen on Sauna Use for the Prevention of Cardiovascular & Alzheimer’s Disease https://www.foundmyfitness.com/episodes/jari-laukkanen Dr. Charles Raison on Depression, the Immune-Brain Interface & Whole-Body Hyperthermia https://www.foundmyfitness.com/episodes/charles-raison

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