OTAVA Ltd
400 Applewood Crescent, Unit 100 L4K 0C3 Vaughan, ON, Canada

We would like to offer you SARS-CoV-2 Nonstructural Protein 14 (NSP14) Targeted Library which contains 1490 compounds. The library has been designed with flexible docking of Drug-like Collection into active sites of SARS-CoV-2 NSP14 exoribonuclease and guanine-N7-methyltransferase domains. All compounds are in stock, cherry-picking is available. The library is intended for screening projects to find compounds with activity against SARS-CoV-2. Find more: https://bit.ly/3lK8pWs... SARS-CoV-2 Targeted Libraries: https://bit.ly/2WS8b4U To find another Targeted library: http://bit.ly/2NrJWJo Design your target-focused library: http://bit.ly/2FKg2tA #Covid2019 #otava #organicchemistry #drugsynthesis #science #openscience #research #drugdiscovery #chemicals #CompoundsforHTS #Chemicalbuildingblocks #Fragmentlibraries #Targetedlibraries #Drugdiscoveryservices #nsp14 #exoribonuclease #guanine-N7-methyltransferase

In view of the complex nature of Alzheimer’s Disease, it becomes clear that pharmacology with drugs targeting different sites could be the most potent strategy to design new drugs to treat #Alzheimer. Supporting AD-associated research and related drug development projects, Otava offers a series of Alzheimer's disease Targeted Libraries https://bit.ly/3iKxyPQ that were designed using modern Ligand-based and Receptor-based approaches. This library collection includes activities... of two main Alzheimer's treatment categories: (I) disease-modifying treatments that target and reduce the secondary pathologies of the disease, leading to the cessation or the reversal of the disease progression; and (II) symptomatic treatments that treat the tertiary cognitive symptoms of the disease and protect from further cognitive decline. All the targeted libraries contain molecules with increased potential for CNS bioavailability. Feel free to contact us directly or send your inquiry to [email protected] -The libraries contain drug-like compounds only - All the compounds are in stock - Cherry picking is available To find more https://bit.ly/3iKxyPQ To find another Targeted library: http://bit.ly/2NrJWJo Design your target-focused library: http://bit.ly/2FKg2 #Covid2019 #otava #organicchemistry #drugsynthesis #science #openscience #research #drugdiscovery #chemicals #CompoundsforHTS #Chemicalbuildingblocks #Fragmentlibraries #Targetedlibraries #Drugdiscoveryservices

One of the major objectives of the Otava team over the last years has been to develop chemical strategies and modern drug discovery methodologies aiming to find potent small compounds with modulating activity toward Alzheimer's Disease. Alzheimer is neurodegenerative progressive disease and has an obscure pathogenesis, thus the finding of new drugs is still in demand. Otava offers a list of biologically active inhibitors presented below that displayed promising anti-Alzheimer... properties. These compounds are available for prompt delivery and may be re-synthesized up to a kilo scale. The chemical optimization and custom synthesis are also applicable. To order the biochemicals please send your inquiry to [email protected] or send request in direct message. To find more https://bit.ly/3iKxyPQ Custom synthesis services from Otava http://bit.ly/2wbJcjd Biochemicals from Otava http://bit.ly/382Qovr Structure search http://bit.ly/32rIHOh #Covid2019 #otava #organicchemistry #drugsynthesis #science #openscience #research #drugdiscovery #chemicals #CompoundsforHTS #Chemicalbuildingblocks #Fragmentlibraries #Targetedlibraries #Drugdiscoveryservices

We would like to offer you SARS-CoV-2 Endoribonuclease Targeted Library, which contains 626 compounds with predicted activity against this enzyme. The library has been designed with receptor-based virtual screening (flexible docking of Drug-like Collection into endoribonuclease active site) using crystal structure (PDB ID: 6VWW) of SARS-CoV-2 NSP15. The library comprises in stock drug-like compounds only, cherry-picking is available. It is intended for screening projects to f...ind compounds with activity against SARS-CoV-2. Find more: https://bit.ly/3hPqGzC SARS-CoV-2 Targeted Libraries: https://bit.ly/2WS8b4U To find another Targeted library: http://bit.ly/2NrJWJo Design your target-focused library: http://bit.ly/2FKg2tA #Covid2019 #otava #organicchemistry #drugsynthesis #science #openscience #research #drugdiscovery #chemicals #CompoundsforHTS #Chemicalbuildingblocks #Fragmentlibraries #Targetedlibraries #Drugdiscoveryservices #nsp13 #helicase

SARS-CoV-2 Helicase (NSP13) Targeted Library Screening compounds for drug discovery projects related to coronavirus disease 2019 (COVID-19) We would like to offer you SARS-CoV-2 Helicase Targeted Library, which contain 1170 compounds with predicted activity against this protein. The library has been designed with receptor-based virtual screening (flexible docking of Drug-like Collection into helicase active site) using the homology model of SARS-CoV-2 NSP13.... The library comprises in stock drug-like compounds only, cherry-picking is available. It is intended for screening projects to find compounds with activity against SARS-CoV-2. Find more: https://bit.ly/3fSVn6N SARS-CoV-2 Targeted Libraries: https://bit.ly/2WS8b4U To find another Targeted library: http://bit.ly/2NrJWJo Design your target-focused library: http://bit.ly/2FKg2tA #Covid2019 #otava #organicchemistry #drugsynthesis #science #openscience #research #drugdiscovery #chemicals #CompoundsforHTS #Chemicalbuildingblocks #Fragmentlibraries #Targetedlibraries #Drugdiscoveryservices #nsp13 #helicase