Ranomics
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How genomics and bioinformatics help in drug discovery for COVID-19 #genomics #drugdiscovery #covid19 https://bit.ly/33XWtss

How genomics and bioinformatics help in drug discovery for COVID-19 #genomics #drugdiscovery #covid19 https://bit.ly/33XWtss

Welcome to the Virosphere: "We have to understand what is out there" https://www.nytimes.com///viruses-coranavirus-biology.html

Interesting work from the Jacob Corn lab today at #KSgenome highlighted that Cas9 binding kinetics to DNA is modulated by the FACT complex in human cells. Also, great insights into how gene editing may require a tissue-specific approach based on the expression profile of human DNA damage repair proteins. Keystone Symposia on Molecular and Cellular Biology

Great #KSgenome morning talk by Tango Therapeutics. Important lessons in clinical trial strategy by Alan Huang. Patient stratification for the herceptin trial using HER2 marker reduced the number of required patients by as much as 10-fold and shortened trial by as much as 300 months.

'EvolvR is a next gen tool for directed evolution'. David Schaffer talked about EvolvR, a platform he developed by tagging nickase Cas9 with an error prone DNA polymerase, last night at #KSgenome #KScelltherapy Keystone Symposia on Molecular and Cellular Biology

Can we make the antibiotic market great again? https://endpts.com/can-we-make-the-antibiotic-market-great/

48 new drugs approved in 2019 https://cen.acs.org//drug-development/new-drugs-2019/98/i3

Great perspective on '-omics' and drug discovery http://www.drugdiscovery.net//omics-data-so-where-is-the-/

Suzanne Lee talks about "biofabrication" and how it could help us replace major sources of waste, like plastic and cement, with sustainable and eco-friendly alternatives. https://www.ted.com//suzanne_lee_why_biofabrication_is_the

Bacteria and sand can be combined to form a living material that acts like concrete. https://www.the-scientist.com//image-of-the-day--living-co

University of Toronto scientists could help people quit smoking by targeting 'disgust' receptors https://www.ctvnews.ca//how-scientists-could-help-people-q

University of New Hampshire researchers have reported the first structural model for a key enzyme, and its activating protein, that can play a role in some genetically inherited eye diseases like retinitis pigmentosa and night blindness. https://phys.org//2020-01-protein-inherited-retinal-diseas

"The cancer death rate in the United States fell 2.2 percent in 2017 the biggest single-year drop ever reported propelled by gains against lung cancer" https://www.washingtonpost.com//cancer-death-rate-posts-/