Skye Blue Publications
1440 Barberry Drive V3B 1G3 Port Coquitlam, BC, Canada

On the advertising front to help run our various websites, good news guys! Both our outlets with Hum-Molgen.org and Wordpress.com have been running adverts with our feature blogs, a great privilege indeed that gives us a lot of satisfaction for all that hard work research and publishing them on the 'Net! Congratulations again to "SkyeBlue"!

Recently our author made a commitment to write a short review article on low-quality feeds and the low protein problem. See entry for this below: http://www.kzoo.edu/beli/article/danny-agustin-flores-80-2/ . We have decided to submit this short review in the next short while, maybe by early of next year 2021. (The two other shorter communications are now featured as blogs published with the "Medica Communications(1-9)" series webpages on the portal site: http://www.hum-mol...gen.de . Plse. look up this webpage(s) (from 1-9) on the topic of functional amino acid (FAA) feeding and lower-cholesterol eggs.) The short review mentioned here will begin with discussing the use of feeding low quality feeds in tropical countries and then with lower quality protein silages in temperate climes outlining their various qualities or characteristics as classified. Then moves into theories on factors determining microbial rumen protein synthesis and presents an list of "tool box" of "interventives", for e. g., manipulating buffering capacity (Bc) in silages to maintain a lower pH, use of probiotics with gene editing and advanced biocontainment using the porin mechanism and cell model, and feeding some of the recently investigated functional amino acids like tyrosine (TYR) and histidine (HIS) with arginine in humans and projecting needed research for meat and dairy cattle. If you want to ff. us as we develop the MS most likely with a journal of food and agriculture with publisher Elsevier B.V. in the Netherlands, tune in here to Facebook.com for updates. This short review will fulfill in part the publications list stipulated for our Principal, Danny Agustin Flores.

Three approaches for studying, as an e. g., the peptide/amino acid uptake problem based on availability in the rumen digesta's milieu are: a) via process innovation approach such as using parameter or data gathering via Rusitec(R)- the artificial rumen device, b) modeling which we have begun, an area we would like to advance involving solving the lowering of shell egg cholesterol in terms of further study of metabolic membrane transport processes with chicken or other poultr...y, and finally (c) in vivo approaches through use of whole animalia as with dosing sampling to measure parameters involving stable isotope labelling, in this case with 15N for peptide/amino acids uptake into microbial cell protein synthesis. Further to this problem, is the study of how peptide composition and secondary structure affects uptake in relation to structure and function of porins, viz. affinity, rate of transport per amino acid residue, and the type of mechanism and structure of porins in cell membranes (e. g. pentapeptides and hexapeptides).

Osmo-pharming which we picked up "on the wire" at Osmopharm SA (a Swiss company) is reworked here for presentation at "SkyeBlue" is referred to collectively as resin-based protected or slow-release amino acids / peptides for rumen stomach applications in livestock (a ground-breaking discovery for "SkyeBlue"). Resin-based shift in digestion and absorption with protected release of bioactive peptides regulating vasodilation in humans has already been studied, developed and manu...factured in Japan. GMO-based osmotic pressured delivery of seco-steroidals into hydroponically-raised (sub- or marine-) plants for conversion to VitD agonists (or variants to VitD) involving ion-exchange resins is also being proposed here at "SkyeBlue." The technique averred to here is "I.V. tapping" in the stem-root junction and will be done sub-hydroponically using skilled labour in Japan/Philippines. This piece of information will be annexured on D. A. Flores' Senior Individualized Project (SIP) 1980's at Kalamazoo College, MI USA. See more