Treventis
60 Leonard Ave 4KD472 M5T 0S8 Toronto, ON, Canada

Can linguistic testing be a useful tool for predicting onset of #Alzheimers prior to an actual clinical diagnosis of impairment? This fascinating study uses a baseline of patients from the Framingham Heart Study, looking specifically at linguistic variables from given tests (namely the Cookie Theft task). Half of the participants in the test set developed AD symptoms before 85 years. #Pfizer #IBM #NaturalistProbing #FraminghamHeartStudy... https://www.thelancet.com//PIIS2589-5370(20)30327/fulltext See more

I'm picking up good vibrations on this one! Swiss researchers report on their use of #ultrasound for #DrugDelivery in the brain using a #LipidCarrier. "When the drug-carrier combo reaches the right spot, the team hits it with a salvo of ultrasound waves. This both locks the carrier in place and allows the researchers to control the drug's release." Way cool! https://www.fiercepharma.com//picking-up-good-vibrations-e

Untangling the plaque accumulation web of postmortem #Alzheimers patients is the focus of this study. Using Tandem Mass Tag (#TMT), #Tandem mass spectrometry (LC-MS/MS) and Immobilized metal affinity chromatography (IMAC), (aka a lot of high tech) to develop #proteome and #phosphoproteome dataset which will may be useful in identifying #biochemical, #cellular and #SignalingPathways altered during AD progression. #TandemMassTag #TandemMassSpectrometry #ImmobolizedMetalAffi...nityChromatography #treventis https://www.nature.com/articles/s41597-020-00650-8 See more

Treventis will be participating in "Clinical Trials in Alzheimer's Disease Nov 4-6, 2020". Anyone else attending? Please let us know here or by email [email protected] https://www.ctad-alzheimer.com/

Are #Alzheimers and #depression comorbidities or symptoms of the other? Study suggests modest or no clinical benefit to AD patients of #antidepressants. Looks at relationship between antidepressant drugs, #A peptide & etiology of depression in AD patients.https://link.springer.com/ch/10.1007%2F978-3-030-42667-5_10

#Alzheimers #Parkinsons and #StemCellTherapy. This paper gives a good overview of the state of research, including investigations into preclinical stem cell transplantation for AD and PD. #StemCellTransplantation #RegenerativeMedicine #StemCells #miRNA... https://www.sciencedirect.com///abs/pii/S0925443919302212 See more