Dentistry Students for Antimicrobial Stewardship Society

The increasing prevalence of antimicrobial resistance around the world has made the discovery of new antibiotics an important global health objective. Cryptic/silent biosynthetic gene clusters (BGCs), which have been revealed through genome mining techniques, provide a ray of hope in the field of natural product discovery. The mini-review below discusses the vast potential of Streptomyces species in producing novel antibiotics as a result of identifying these silent BGCs through genome mining techniques. However, several challenges remain, in regards to developing methods that can induce the large scale production of these mysterious compounds.

An informative systematic review of recent research regarding the use of antimicrobial nanoparticles in various dental fields, including restorative dentistry, periodontics, orthodontics and implantology. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470852/

:v Statistics based on 30 antimicrobial susceptibility studies of C. difficile clinical isolates reveal that resistance to clindamycin (8.3% to 100%), cephalosporins (51%), erythromycin (13% to 100%), and fluoroquinolones (47%) is commonly observed. https://pubmed.ncbi.nlm.nih.gov/28404671/

Informative retrospective cohort study on antibiotic prophylaxis in dentistry between 2011 and 2015: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547109/

DSASS is back for another academic year! Keep your eyes open for updates and promotions for exciting upcoming events. In the meantime, stay up-to-date with the latest news on antimicrobial resistance from the World Health Organization's website here: https://www.who.int/health-topics/antimicrobial-resistance